Prof. Dr. med. Johannes Ruef

1993

Ludolf Krehl Preis (1.Preis) der Südwest-Deutschen Gesellschaft für Innere Medizin, in der Sektion medizinische Dissertationen.

1997

2. Preis, Astra-Merck Third Annual Cardiovascular Young Investigator’s Forum, Washington, in der Sektion „Basic Science“.

1998

Förderpreis der Deutschen Herzstiftung.

1999

Finalist and honorable mentioning, American College of Cardiology Young Investigator Award Competition, New Orleans.

1)

Ruef J, Hu ZY, Yin L-Y, Hanson SR, Kelly AB, Harker LA, Rao GN, Runge MS, Patterson C. Induction of vascular endothelial growth factor in balloon-injured baboon arteries: a novel role for reactive oxygen species in atherosclerosis. Circulation Research 1997; 81: 24-33.

2)

Ruef J, Rao GN, Li F, Bode C, Patterson C, Bhatnagar A, Runge MS. Induction of rat aortic smooth muscle cell growth by the lipid peroxidaton product 4-hydroxy- 2-nonenal. Circulation 1998, 97: 1071-1078.

3)

Ruef J, Papadaki M, Nguyen TK, Patterson C, Eskin SG, McIntire LV, Runge MS. Differential regulation of protease activated receptor-1 and tissue plasminogen activator expression by shear stress in vascular smooth muscle cells. Circulation Research, 1998, 83: 1027-1034 (2 Erstautoren).

4)

Ruef J, Patterson C, Madamanchi NR, Barry-Lane P, Hu Z, Horaist C, Ballinger CA, Brasier AR, Bode C, Runge MS. Stimulation of a vascular smooth muscle cell NAD(P)H oxidase by thrombin. Evidence that p47phox may participate in forming this oxidase in vitro and in vivo. J Biol Chem 1999; 274: 19814-19822 (2 Erstautoren).

5)

Ruef J, Nordt TK, Peter K, Runge MS, Kübler W, Bode C. A bispecific antifibrin- antiplatelet urokinase conjugate (BAAUC) induces enhanced clot lysis and inhibits platelet aggregation. Thrombosis Haemostasis, 1999, 82: 109-114.

6)

Ruef J, Meshel AS, Hu Z, Horaist C, Ballinger C, Thompson LJ, Subbarao VD, Dumont JA, Paterson C. Flavopiridol inhibits smooth muscle cell proliferation in vitro and neointimal formation in vivo after carotid injury in the rat. Circulation 1999, 100: 659-665.

7)

Ruef J, Liu S-Q, Bode C, Tocchi M, Srivastava s, Runge MS, Bhatnagar A. Involvement of aldose reductase in vascular smooth muscle cell growth and lesion formation following arterial injury. Arterioscl Thromb Vascul Biol 2000, 20: 1745-1752.

8)

Ruef J, Kuehnl P, Meinertz T, Merten M. The complement factor properdin induces formation of platelet-leukocyte aggregates via leukocyte activation. Platelets 2008; 19: 359-364.

9)

Ruef J. One year follow-up after implantation of the EverFlexTM nitinol stent in long lesions of the superficial femoral artery. Angiology 2009, 60: 31-35.

10)

Ruef J, Störger H, Schwarz F, Haase J. Increased restenosis rates 12 months after coronary implantation of the sirolimus-eluting YUKON-choice stent compared to the paclitaxel-eluting TAXUS Stent. Clin. Cardiol. 2010; 33: E33-38.